David A Isenberg Selected Research

Dermatomyositis (Dermatopolymyositis)

1/2018	CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.
1/2017	Rituximab in the treatment of inflammatory myopathies: a review.
11/2013	Rituximab as an effective alternative therapy in refractory idiopathic inflammatory myopathies.

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David A Isenberg Research Topics

Disease

78	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2022 - 06/2002
16	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 06/2022 - 02/2003
13	Rheumatoid Arthritis 01/2021 - 05/2003
12	Lupus Nephritis 08/2020 - 03/2004
9	Rheumatic Diseases (Rheumatism) 01/2020 - 05/2006
8	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 05/2006
8	Thrombosis (Thrombus) 01/2021 - 06/2010
8	Myositis (Idiopathic Inflammatory Myopathies) 01/2020 - 01/2006
5	Neoplasms (Cancer) 12/2021 - 01/2006
5	Infections 01/2018 - 12/2002
4	Inflammation (Inflammations) 01/2021 - 08/2007
4	Nephritis 01/2021 - 04/2008
4	Chronic Kidney Failure (Chronic Renal Failure) 11/2020 - 04/2008
4	Vasculitis (Vasculitides) 05/2019 - 01/2003
4	Proteinuria 01/2016 - 07/2004
3	Atherosclerosis 03/2021 - 04/2010
3	Polymyositis 01/2020 - 11/2013
3	Hypertension (High Blood Pressure) 01/2019 - 12/2006
3	Dermatomyositis (Dermatopolymyositis) 01/2018 - 11/2013
3	Necrosis 01/2016 - 08/2004
2	Headache (Headaches) 12/2021 - 11/2013
2	Hemorrhage 01/2021 - 09/2016
2	Thrombocytopenia (Thrombopenia) 01/2021 - 02/2008
2	Psoriatic Arthritis 01/2021 - 11/2020
2	Thrombophilia 10/2020 - 06/2010
2	Lymphoma (Lymphomas) 01/2020 - 06/2011
2	Venous Thromboembolism 01/2017 - 09/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2016 - 08/2007
2	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2005 - 07/2004
1	Breast Neoplasms (Breast Cancer) 12/2021
1	Skin Neoplasms (Skin Cancer) 12/2021
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 05/2021
1	Atherosclerotic Plaque (Atheroma) 03/2021
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2021
1	Activated Protein C Resistance (APC Resistance) 01/2021
1	COVID-19 10/2020
1	Leukemia 01/2020
1	Communicable Diseases (Infectious Diseases) 01/2020

Drug/Important Bio-Agent (IBA)

24	AutoantibodiesIBA 01/2020 - 06/2002
19	Rituximab (Mabthera)FDA Link 01/2022 - 07/2009
12	AntibodiesIBA 01/2020 - 03/2004
12	Immunoglobulin G (IgG)IBA 01/2018 - 03/2005
9	Proteins (Proteins, Gene)FDA Link 11/2020 - 06/2002
8	LipidsIBA 03/2021 - 05/2003
6	belimumabIBA 12/2021 - 01/2015
6	Antiphospholipid AntibodiesIBA 10/2020 - 02/2003
5	Pharmaceutical PreparationsIBA 06/2022 - 12/2004
5	DNA (Deoxyribonucleic Acid)IBA 01/2016 - 03/2005
4	Complement System Proteins (Complement)IBA 01/2021 - 04/2008
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 08/2004
4	CytokinesIBA 01/2021 - 08/2004
4	Biological ProductsIBA 01/2021 - 12/2009
4	C-Reactive ProteinIBA 05/2019 - 01/2004
4	Monoclonal AntibodiesIBA 01/2018 - 07/2007
4	AntigensIBA 12/2017 - 01/2004
4	SteroidsIBA 01/2017 - 07/2009
4	anti-dsDNA autoantibodyIBA 01/2017 - 12/2005
4	Phospholipids (Phosphatides)FDA LinkGeneric 12/2016 - 02/2003
3	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2021 - 11/2013
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2021 - 02/2008
3	Biomarkers (Surrogate Marker)IBA 03/2021 - 01/2018
3	AnticoagulantsIBA 01/2021 - 01/2017
3	Warfarin (Coumadin)FDA LinkGeneric 01/2021 - 09/2016
3	Mycophenolic Acid (Cellcept)FDA LinkGeneric 08/2020 - 01/2008
3	Ligases (Synthetase)IBA 01/2020 - 11/2013
3	Antinuclear AntibodiesIBA 01/2019 - 03/2004
3	Lupus Coagulation Inhibitor (Lupus Anticoagulant)IBA 10/2018 - 07/2004
3	Thromboplastin (Tissue Factor)IBA 01/2018 - 06/2010
3	Arginine (L-Arginine)FDA Link 07/2007 - 02/2003
2	obinutuzumabIBA 01/2022 - 01/2017
2	Antimalarials (Antimalarial Agents)IBA 12/2021 - 11/2013
2	GlucocorticoidsIBA 12/2021 - 11/2012
2	Immunosuppressive Agents (Immunosuppressants)IBA 12/2021 - 04/2008
2	TACI receptor-IgG Fc fragment fusion proteinIBA 11/2021 - 08/2015
2	Anti-Idiotypic AntibodiesIBA 01/2021 - 04/2008
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2021 - 11/2020
2	Nuclear Antigens (Extractable Nuclear Antigens)IBA 01/2021 - 01/2007
2	InterferonsIBA 01/2018 - 01/2016
2	Adalimumab (Humira)FDA Link 01/2018 - 10/2012
2	Thrombin FDA Link 01/2017 - 09/2016
2	RivaroxabanIBA 01/2017 - 09/2016
2	Immunoglobulins (Immunoglobulin)IBA 01/2017 - 10/2013
2	Nucleosomes (Nucleosome)IBA 10/2009 - 01/2005
2	ActininIBA 10/2009 - 03/2004
2	Antigen-Antibody Complex (Immune Complex)IBA 01/2007 - 05/2006
2	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 05/2006 - 01/2003
2	Complementarity Determining Regions (Complementarity Determining Region)IBA 09/2003 - 02/2003
2	AsparagineIBA 09/2003 - 02/2003
2	Lysine (L-Lysine)FDA Link 09/2003 - 02/2003
1	Inosine Triphosphate (ITP)IBA 05/2021
1	Vitamin K FDA Link 01/2021
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2021
1	Protein CIBA 01/2021
1	Vitamin D FDA LinkGeneric 01/2021
1	CreatinineIBA 11/2020
1	ibrutinibIBA 01/2020

Therapy/Procedure

31	Therapeutics 12/2021 - 10/2002
4	Biological Therapy 11/2020 - 03/2014
2	Secondary Prevention 09/2016 - 02/2010
1	Immunomodulation 01/2021